abstract：BACKGROUND:physical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death. METHODS:in the Women's Health Initiativ...

journal_title：Age and ageing

authors： Saquib N,Brunner R,Desai M,Kroenke C,Martin LW,Daviglus M,Allen NB,Robinson J,Tindle H,Stefanick ML

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:our aim was to study the relationship between HbA1c and cardiovascular morbidity and all-cause mortality among older insulin-treated patients with type 2 diabetes (T2D) after adjustment for multiple confounders. METHODS:data for 4589 adults with T2D (>65 years) on insulin treatment were sourced from 532 UK ...

journal_title：Age and ageing

authors： Anyanwagu U,Mamza J,Donnelly R,Idris I

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:early mobilization after hip fracture (HF) is an important predictor of outcome, but knowledge of the consequences of not achieving the pre-fracture basic mobility status in acute hospital recovery is sparse. OBJECTIVE:we examined whether the regain of pre-fracture basic mobility status evaluated with the c...

journal_title：Age and ageing

authors： Kristensen MT,Öztürk B,Röck ND,Ingeman A,Palm H,Pedersen AB

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:the impact of retirement on physical health is an important focus of ageing research; however, research findings vary greatly. To investigate under what conditions retirement might benefit health, we examined physical functioning 8 years pre- and post-retirement. METHODS:using longitudinal data from the New...

journal_title：Age and ageing

authors： Szabó Á,Allen J,Stephens C,Alpass F

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:exercise therapy is highly recommended for falls prevention in older adults; however, poor exercise adherence may limit treatment effectiveness. OBJECTIVE:to assess the effectiveness of interventions to improve exercise adherence for community-dwelling adults (aged over 65 years), at risk of falling. METHO...

journal_title：Age and ageing

authors： Hughes KJ,Salmon N,Galvin R,Casey B,Clifford AM

更新日期：2019-03-01 00:00:00

abstract：Background:the association between pain characteristics and frailty risk is uncertain. Objective:to investigate the separate impact of the frequency, intensity and location of pain on frailty risk and its possible mechanisms. Methods:prospective cohort of 1505 individuals ≥63 years followed between 2012 and 2015 in S...

journal_title：Age and ageing

authors： Rodríguez-Sánchez I,García-Esquinas E,Mesas AE,Martín-Moreno JM,Rodríguez-Mañas L,Rodríguez-Artalejo F

更新日期：2019-01-01 00:00:00

abstract：:This invited article is drawn from the content of the Marjory Warren Lecture given by John Gladman at the British Geriatrics Society Spring Meeting in 2018, entitled 'The Meaning of Life Expectancy'. ...

journal_title：Age and ageing

authors： Gladman JRF

更新日期：2019-01-01 00:00:00

abstract：Background:making informed decisions about cancer care provision for older cancer patients can be challenging and complex. Evidence suggests cancer care varies by age, however the relationship between age and care experiences from diagnosis to death for cancer patients within the UK has not previously been examined in ...

journal_title：Age and ageing

authors： Craigs CL,Bennett MI,Hurlow A,West RM,Ziegler LE

更新日期：2018-11-01 00:00:00

abstract：Background:Pain and delirium are common in people with dementia admitted to hospitals. These are often under-diagnosed and under-treated. Pain is implicated as a cause of delirium but this association has not been investigated in this setting. Objective:To investigate the relationship between pain and delirium in peop...

journal_title：Age and ageing

authors： Feast AR,White N,Lord K,Kupeli N,Vickerstaff V,Sampson EL

更新日期：2018-11-01 00:00:00

abstract：Background:pain is prevalent in frail older adults; however, the association of pain and frailty has not been evaluated yet by a systematic assessment of prospective longitudinal studies. Objective:we aimed to assess the association of persistent pain as a risk factor for frailty incidence, using data from longitudina...

journal_title：Age and ageing

authors： Saraiva MD,Suzuki GS,Lin SM,de Andrade DC,Jacob-Filho W,Suemoto CK

更新日期：2018-11-01 00:00:00

abstract：Background:a trend towards decline in disability has been reported in older adults, but less is known about corresponding temporal trends in measured physical functions. Objective:to verify these trends during 2001-16 in an older Swedish population. Methods:functional status was assessed at three occasions: 2001-04 (...

journal_title：Age and ageing

authors： Santoni G,Angleman SB,Ek S,Heiland EG,Lagergren M,Fratiglioni L,Welmer AK

更新日期：2018-09-01 00:00:00

abstract：Objective:to investigate whether cognitive impairment, measured early after Emergency Department (ED) arrival and irrespective of its cause, is independently associated with functional decline or mortality after 3 and 12 months in older ED patients. Design and setting:a prospective multi-centre cohort study in all Acu...

journal_title：Age and ageing

authors： Lucke JA,de Gelder J,Heringhaus C,van der Mast RC,Fogteloo AJ,Anten S,Blauw GJ,de Groot B,Mooijaart SP

更新日期：2018-09-01 00:00:00

abstract：Objective:to describe differences in care and 30-day mortality of patients admitted with hip fracture on weekends (Saturday-Sunday) compared to weekdays (Monday-Friday), and their relationship to the organisation of care. Methods:data came from the National Hip Fracture Database (NHFD) linked to ONS mortality data on ...

journal_title：Age and ageing

authors： Neuburger J,Currie C,Wakeman R,Georghiou T,Boulton C,Johansen A,Tsang C,Wilson H,Cromwell DA,van der Meulen J

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:care home residents have high healthcare needs not fully met by prevailing healthcare models. This study explored how healthcare configuration influences resource use. METHODS:a realist evaluation using qualitative and quantitative data from case studies of three UK health and social care economies select...

journal_title：Age and ageing

authors： Gordon AL,Goodman C,Davies SL,Dening T,Gage H,Meyer J,Schneider J,Bell B,Jordan J,Martin FC,Iliffe S,Bowman C,Gladman JRF,Victor C,Mayrhofer A,Handley M,Zubair M

更新日期：2018-07-01 00:00:00

abstract：:Falls pose a major threat to the well-being and quality of life of older people. Falls can result in fractures and other injuries, disability and fear and can trigger a decline in physical function and loss of autonomy. This article synthesises recent published findings on fall risk and mobility assessments and fall p...

journal_title：Age and ageing

authors： Lord SR,Close JCT

更新日期：2018-07-01 00:00:00

abstract：Background:measuring the complex needs of care home residents is crucial for resource allocation. Hospital patient administration systems (PAS) may not accurately identify admissions from care homes. Objective:to develop and validate an accurate, practical method of identifying care home resident hospital admission us...

journal_title：Age and ageing

authors： Housley G,Lewis S,Usman A,Gordon AL,Shaw DE

更新日期：2018-05-01 00:00:00

abstract：:This is the second in an occasional series of paired commentaries in Age and Ageing, the Journal of the British Geriatrics Society and the Journal of the American Geriatrics Society (JAGS). The aim is to address issues of current significance and to foster dialogue and increased understanding between academics and cli...

journal_title：Age and ageing

authors： Pollock K,Seymour J

更新日期：2018-05-01 00:00:00

abstract：Background:despite an increasing proportion of older people working beyond State Pension Age (SPA), little is known about neither the motivations for this decision nor whether, and to what extent, working beyond SPA affects quality of life (QoL). Methods:QoL was measured using the CASP-19 scale. Respondents in paid wo...

journal_title：Age and ageing

authors： Di Gessa G,Corna L,Price D,Glaser K

更新日期：2018-05-01 00:00:00

abstract：:Alcohol consumption constitutes a substantial burden of disease. Older people are being admitted to hospital for alcohol problems in increasing numbers. A recent systematic review reports cautious supportive evidence for primary prevention interventions in reducing excessive alcohol consumption in older drinkers, but ...

journal_title：Age and ageing

authors： Crome IB,Crome P

更新日期：2018-03-01 00:00:00

abstract：Background:harmful alcohol consumption is reported to be increasing in older people. To intervene and reduce associated risks, evidence currently available needs to be identified. Methods:two systematic reviews in older populations (55+ years): (1) Interventions to prevent or reduce excessive alcohol consumption; (2) ...

journal_title：Age and ageing

authors： Kelly S,Olanrewaju O,Cowan A,Brayne C,Lafortune L

更新日期：2018-03-01 00:00:00

abstract：Background:general practitioners (GPs) have identified the management of behavioural and psychological symptoms of dementia (BPSD) as a particularly challenging aspect of dementia care. However, there is a paucity of research on why GPs find BPSD challenging and how this influences the care they offer to their patients...

journal_title：Age and ageing

authors： Jennings AA,Foley T,McHugh S,Browne JP,Bradley CP

更新日期：2018-03-01 00:00:00

abstract：Background:screening for cognitive impairment in Emergency Department (ED) requires short, reliable tools. Objective:to validate the 4AT and 6-Item Cognitive Impairment Test (6-CIT) for ED dementia and delirium screening. Design:diagnostic accuracy study. Setting/subjects:attendees aged ≥70 years in a tertiary care ...

journal_title：Age and ageing

authors： O'Sullivan D,Brady N,Manning E,O'Shea E,O'Grady S,O 'Regan N,Timmons S

更新日期：2018-01-01 00:00:00

abstract：Introduction:frailty is an increased vulnerability to adverse health outcomes, across multiple physiological systems, with both environmental and genetic drivers. The two most commonly used measures are Rockwood's frailty index (FI) and Fried's frailty phenotype (FP). Material and methods:the present study included 36...

journal_title：Age and ageing

authors： Livshits G,Ni Lochlainn M,Malkin I,Bowyer R,Verdi S,Steves CJ,Williams FMK

更新日期：2018-01-01 00:00:00

abstract：Background:older patients admitted to hospitals are at risk for hospital-acquired morbidity related to immobility. The aim of this study was to implement and evaluate an evidence-based intervention targeting staff to promote early mobilisation in older patients admitted to general medical inpatient units. Methods:the ...

journal_title：Age and ageing

authors： Liu B,Moore JE,Almaawiy U,Chan WH,Khan S,Ewusie J,Hamid JS,Straus SE,MOVE ON Collaboration.

更新日期：2018-01-01 00:00:00

abstract：Background:there is limited data comparing conditions and health service use across care settings in centenarians. To improve health service delivery in centenarians, the aim of this study was to compare the proportion of centenarians who have chronic conditions, take medication and use health care services across diff...

journal_title：Age and ageing

authors： von Berenberg P,Dräger D,Zahn T,Neuwirth J,Kuhlmey A,Gellert P

更新日期：2017-11-01 00:00:00

abstract：Background:diabetes increases the risk of frailty that is a leading cause of disability and premature mortality in older people. Metabolic syndrome (MS) and insulin resistance (IR) are strong risk factors for diabetes and could, thus, lead to frailty. However, the association between MS or IR and frailty has barely bee...

journal_title：Age and ageing

authors： Pérez-Tasigchana RF,León-Muñoz LM,Lopez-Garcia E,Gutierrez-Fisac JL,Laclaustra M,Rodríguez-Artalejo F,Guallar-Castillón P

更新日期：2017-09-01 00:00:00

abstract：Introduction:identifying the most at risk older people in Emergency Departments (EDs) may help guide clinical practice, and service improvement in emergency care, but little is known about how to implement such tools in practice. Methods:consensus building was used to determine the desirable characteristics of a risk ...

journal_title：Age and ageing

authors： Elliott A,Phelps K,Regen E,Conroy SP

更新日期：2017-09-01 00:00:00

abstract：Background:there is growing consensus around the importance of population level approaches which seek to improve public knowledge and awareness of dementia. Aim:to assess knowledge of the relationship between dementia and ageing, and of the risk and protective factors associated with it, among the general public in Ir...

journal_title：Age and ageing

authors： Glynn RW,Shelley E,Lawlor BA

更新日期：2017-09-01 00:00:00

abstract：Background:overactive bladder (OAB) is a common condition in older persons. Antimuscarinic treatment remains the mainstay of treatment of OAB but clinicians have been reluctant to prescribe this to older patients. This study examined efficacy and safety information from patients >65 in fesoterodine trials to reaffirm e...

journal_title：Age and ageing

authors： Wagg A,Arumi D,Herschorn S,Angulo Cuesta J,Haab F,Ntanios F,Carlsson M,Oelke M

更新日期：2017-07-01 00:00:00

abstract：:Solitary fibrous tumour of the pleura (SFTP) is a rare primary tumour of the pleura associated with 4% of cases with a paraneoplastic hypoglycaemia, termed Doege-Potter syndrome (DPS). We report a case of DPS presenting with severe coma in a 90-year-old woman. The cause was a malignant SFTP treated with surgical resec...

journal_title：Age and ageing

authors： Avramenko A,Lahjibi-Paulet H,Gibault L,Roussel A,Grand B,Le Pimpec-Barthes F

更新日期：2017-05-01 00:00:00

abstract：Background:fear of falling (FOF) is a major health concern among community-dwelling older adults that could restrict mobility. Objective:to examine the association of FOF with life-space mobility (i.e. the spatial area a person moves through in daily life) of community-dwelling older adults from five diverse sites. M...

journal_title：Age and ageing

authors： Auais M,Alvarado B,Guerra R,Curcio C,Freeman EE,Ylli A,Guralnik J,Deshpande N

更新日期：2017-05-01 00:00:00

abstract：:The UK has many excellent care homes that provide high-quality care for their residents; however, across the care home sector, there is a significant need for improvement. Even though the majority of care homes receive a rating of 'good' from regulators, still significant numbers are identified as requiring 'improveme...

journal_title：Age and ageing

authors： Hockley J,Harrison JK,Watson J,Randall M,Murray S

更新日期：2017-03-01 00:00:00

abstract：Background/Objective:studies on the association of dementia with specific body composition (BC) components are scarce. Our aim was to investigate associations of BC measures with different levels of cognitive function in late-life. Methods:we studied 5,169 participants (mean age 76 years, 42.9% men) in the AGES-Reykja...

journal_title：Age and ageing

authors： Spauwen PJ,Murphy RA,Jónsson PV,Sigurdsson S,Garcia ME,Eiriksdottir G,van Boxtel MP,Lopez OL,Gudnason V,Harris TB,Launer LJ

更新日期：2017-03-01 00:00:00

abstract：Background:orthostatic hypotension (OH) is a common disabling condition associated with increased morbidity and mortality. Much of the evidence available is derived from younger populations with chronic neurological disease leading to uncertainty for the diagnosis and management of older people. Objective:to provide a...

journal_title：Age and ageing

authors： Frith J,Parry SW

更新日期：2017-03-01 00:00:00

abstract：Background:high cardiorespiratory fitness (CRF) is associated with larger brain volumes but data on sex differences in the association of CRF with brain volumes are scarce. We investigated whether the association of CRF with total grey matter (GM) and white matter volumes as well as medial temporal lobe and striatum vo...

journal_title：Age and ageing

authors： Pentikäinen H,Ngandu T,Liu Y,Savonen K,Komulainen P,Hallikainen M,Kivipelto M,Rauramaa R,Soininen H

更新日期：2017-03-01 00:00:00

abstract：Objective:to investigate a high-intensity functional exercise (HIFE) group in hospitalised older adults. Design:assessor-blinded, randomised-controlled trial. Setting:sub-acute wards at a metropolitan rehabilitation hospital. Participants:older adults ≥65 years (n = 468) able to stand with minimum assistance or less...

journal_title：Age and ageing

authors： Raymond MJ,Jeffs KJ,Winter A,Soh SE,Hunter P,Holland AE

更新日期：2017-03-01 00:00:00

abstract：Background:patient empowerment, through which patients become self-determining agents with some control over their health and healthcare, is a common theme across health policies globally. Most care for older people is in the acute setting, but there is little evidence to inform the delivery of empowering hospital care...

journal_title：Age and ageing

authors： Selman LE,Daveson BA,Smith M,Johnston B,Ryan K,Morrison RS,Pannell C,McQuillan R,de Wolf-Linder S,Pantilat SZ,Klass L,Meier D,Normand C,Higginson IJ

更新日期：2017-03-01 00:00:00

abstract：Objective:To establish a consensus on the care and professional development needs of registered nurses (RNs) employed by UK care homes. Design:Two-stage, online modified Delphi study. Setting and Participants:A panel (n = 352) of individuals with experience, expertise or interest in care home nursing: (i) care home n...

journal_title：Age and ageing

authors： Cooper E,Spilsbury K,McCaughan D,Thompson C,Butterworth T,Hanratty B

更新日期：2017-01-08 00:00:00

abstract：:The world is ageing rapidly. Between 2000 and 2050, the number of people aged ≥65 will double as a proportion of the global population, from 7% to 16%, respectively. By 2050, for the first time in human history, there will be more older people than children (aged 0–14 years) in the population. More distinctive is the ...

journal_title：Age and ageing

authors： van der Cammen TJ,Albayrak A,Voûte E,Molenbroek JF

更新日期：2017-01-05 00:00:00

abstract：:Pulmonary embolism (PE) is a potentially severe diagnosis with high short-term mortality. Recently, age-adjusted cut-off values (age × 10 μg/l) of D-dimer were introduced to improve the diagnostic workup in older patients. In clinical practice, PE is considered 'ruled out' in patients with a non-high clinical probabil...

journal_title：Age and ageing

authors： Stein CE,Keijsers CJ,Bootsma JE,Schouten HJ

更新日期：2016-11-01 00:00:00